Antibiotics have always played an important part in F.I.R.M.A.'s history and development. Sulphamides were the first antibacterial products to be manufactured towards the end of the 1950's, immediately followed by kanamycin, tetracycline, methylene lysine, doxycycline, and dicloxacillin.

An important turning-point was reached with the marketing of the first beta-lactam antibiotic capable of passing through the brain blood barrier, methicillin. The manufacturing and marketing of other important antibiotics, still present on the national reimbursement list, then followed such as cinoxacin, amoxycillin, cephazolin, cefuroxime, cefatrizine, and miocamycin, until arriving at the most recent and valid molecules, ceftazidime and cefixime.